Epinephrine Treatment of Anaphylaxis

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First-aid treatment of anaphylaxis to food: focus on epinephrine.

Avoiding food triggers for anaphylactic reactions (severe acute systemic allergic reactions) is easier said than done. Most episodes of anaphylaxis to food occur unexpectedly in the community in the absence of a health care professional. All individuals at risk should therefore have an emergency action plan in place. The cornerstone of first-aid treatment of anaphylaxis is epinephrine injected ...

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Epinephrine for First-aid Management of Anaphylaxis.

Anaphylaxis is a severe, generalized allergic or hypersensitivity reaction that is rapid in onset and may cause death. Epinephrine (adrenaline) can be life-saving when administered as rapidly as possible once anaphylaxis is recognized. This clinical report from the American Academy of Pediatrics is an update of the 2007 clinical report on this topic. It provides information to help clinicians i...

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Epinephrine for Anaphylaxis: Underutilized and Unavailable

INTRODUCTION Anaphylaxis is a rapidly progressing, potentially life threatening allergic reaction that has been increasing in prevalence, most commonly triggered by foods, medications, and insect stings. Allergies in children are increasingly more common. Unfortunately, anaphylactic reactions are under-recognized, due to overlooked or under-appreciated symptoms, and therefore under-treated with...

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Epinephrine treatment of anaphylaxis: an extraordinary case of very late acute stent thrombosis.

A 78-year-old man experienced marked angioedema of his face and tongue following ingestion of chocolatecoated peanuts. Paramedics administered 0.5 mg of intramuscular epinephrine within half an hour of symptom onset with rapid relief of symptoms and subsidence of the swelling. On route to the local Emergency Department the patient suddenly became pale, nauseous, and began sweating profusely. Th...

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A preliminary study of intranasal epinephrine administration as a potential route for anaphylaxis treatment.

BACKGROUND The intranasal (IN) administration of epinephrine could be an alternative route for anaphylaxis treatment. Although IN epinephrine absorption has been demonstrated in animals, such data in humans are still lacking. OBJECTIVE To study the pharmacokinetics of IN epinephrine absorption in humans. METHODS Each healthy adult (n = 5) was administered IN saline, IN epinephrine at variou...

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ژورنال

عنوان ژورنال: Circulation: Cardiovascular Interventions

سال: 2009

ISSN: 1941-7640,1941-7632

DOI: 10.1161/circinterventions.108.820266